Extensively Drug-resistant Tuberculosis(XDR-TB)

Multidrug resistant TB and extensively drug resistant TB

Resistance to anti-TB drugs is not an emerging phenomenon, but a process closely related to the implementation of chemotherapy against TB. Clinical evidence to prove the development of resistance to anti-TB drugs was provided by the Medical Research Council team in 1948, shortly after using streptomycin in (as?) monotherapy for TB treatments 1. As isoniazid, PAS and streptomycin were first used...

Extensively drug resistant tuberculosis (XDR-TB): A potential threat

Emergence of extensively drug resistant tuberculosis (XDR-TB) has been reported by more than 55 countries. XDR-TB is considered as untreatable and highly fatal disease. In developing countries like India, number of cases of multi-drug resistant tuberculosis (MDR-TB) and XDR-TB are increasing. Emergence of resistance to Isoniazid and Rifampicin, the two most effective and well tolerated agents, ...

Extensively drug-resistant tuberculosis (XDR-TB) raises challenges in TB control in Taiwan.

Since last year, Mr Lee, a 56-year-old tuberculosis (TB) patient, has been locked up indefinitely, perhaps for the rest of his life. Prior to that, he had escaped from hospital before the end of his multiple drug-resistant TB treatment, and had strongly expressed unwillingness to return to hospital for treatment. Taiwan’s Centers for Disease Control (CDC) announced his name, and he became a wan...

Extensively drug-resistant tuberculosis.

Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any fluoroquinolone, and at least one of three injectable second-line drugs (amikacin, capreomycin, or kanamycin). The definition has applicable clinical value and has allowed for more uniform surveillance in varied international settings...

Multi-Drug/Extensively Drug Resistant Tuberculosis (Mdr/Xdr-Tb): Renewed Global Battle Against Tuberculosis?